Cocaine promotes oxidative stress and microglial-macrophage activation in rat cerebellum

Different mechanisms have been suggested for cocaine neurotoxicity, including oxidative stress alterations. Nuclear factor kappa B (NF-κB), considered a sensor of oxidative stress and inflammation, is involved in drug toxicity and addiction. NF-κB is a key mediator for immune responses that induces...

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Bibliographic Details
Main Authors: López-Pedrajas, Rosa, Ramírez-Lamelas, Dolores T., Muriach, Borja, Sánchez-Villarejo, María V., Almansa, Inmaculada, Vidal-Gil, Lorena, Romero, Francisco J., Barcia, Jorge M., Muriach, María
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516895/