Cocaine promotes oxidative stress and microglial-macrophage activation in rat cerebellum
Different mechanisms have been suggested for cocaine neurotoxicity, including oxidative stress alterations. Nuclear factor kappa B (NF-κB), considered a sensor of oxidative stress and inflammation, is involved in drug toxicity and addiction. NF-κB is a key mediator for immune responses that induces...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516895/ |