Blocking neutrophil integrin activation prevents ischemia–reperfusion injury

Blocking neutrophil integrin activation prevents ischemia–reperfusion injury

Yago et al. find that neutrophils expressing a talin1 mutant that perturbs integrin activation fail to undergo chemokine-induced arrest, spreading, and migration, thus preventing ischemia–reperfusion injury.

Bibliographic Details
Main Authors: Yago, Tadayuki, Petrich, Brian G., Zhang, Nan, Liu, Zhenghui, Shao, Bojing, Ginsberg, Mark H., McEver, Rodger P.
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516797/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516797/

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