The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells

Among the identified thousands of circular RNAs (circRNA) in humans and animals, Cdr1as (also known as CiRS-7) was recently demonstrated to act as a powerful miR-7 sponge/inhibitor in developing midbrain of zebrafish, suggesting a novel mechanism for regulating microRNA functions. MiR-7 is abundantl...

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Bibliographic Details
Main Authors: Xu, Huanyu, Guo, Sen, Li, Wei, Yu, Ping
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515639/