Fibrinolysis-independent role of plasmin and its activators in the haematopoietic recovery after myeloablation

Proteinases have been implicated in the mobilization of haematopoietic progenitor cells (HPCs) from the bone marrow (BM). Here, we report the involvement of the plasminogen (Plg) system in the haematopoietic recovery following chemotherapy. By using gene-deficient mice, we found that plasmin and its...

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Bibliographic Details
Main Authors: Tjwa, Marc, Moura, Rute, Moons, Lieve, Plaisance, Stephane, Mol, Maria De, Jansen, Sandra, Dewerchin, Mieke, Verfaillie, Catherine, Carmeliet, Peter
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515073/