Hypothalamic sensing of circulating lactate regulates glucose production

Emerging studies indicate that hypothalamic hormonal signalling pathways and nutrient metabolism regulate glucose homeostasis in rodents. Although hypothalamic lactate-sensing mechanisms have been described to lower glucose production (GP), it is currently unknown whether the hypothalamus senses lac...

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Bibliographic Details
Main Authors: Kokorovic, Andrea, Cheung, Grace WC, Rossetti, Luciano, Lam, Tony KT
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515055/