A statistical physics perspective on alignment-independent protein sequence comparison

Motivation: Within bioinformatics, the textual alignment of amino acid sequences has long dominated the determination of similarity between proteins, with all that implies for shared structure, function and evolutionary descent. Despite the relative success of modern-day sequence alignment algorithm...

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Bibliographic Details
Main Authors: Chattopadhyay, Amit K., Nasiev, Diar, Flower, Darren R.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514925/