A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen

In the HIV vaccine field, there is a need to produce highly immunogenic forms of the Env protein with the capacity to trigger broad B and T-cell responses. Here, we report the generation and characterization of a chimeric HIV-1 gp120 protein (termed gp120-14K) by fusing gp120 from clade B with the v...

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Bibliographic Details
Main Authors: Vijayan, Aneesh, García-Arriaza, Juan, C. Raman, Suresh, Conesa, José Javier, Chichón, Francisco Javier, Santiago, César, Sorzano, Carlos Óscar S., Carrascosa, José L., Esteban, Mariano
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514760/