Predicting Variabilities in Cardiac Gene Expression with a Boolean Network Incorporating Uncertainty

Gene interactions in cells can be represented by gene regulatory networks. A Boolean network models gene interactions according to rules where gene expression is represented by binary values (on / off or {1, 0}). In reality, however, the gene’s state can have multiple values due to biological proper...

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Bibliographic Details
Main Authors: Grieb, Melanie, Burkovski, Andre, Sträng, J. Eric, Kraus, Johann M., Groß, Alexander, Palm, Günther, Kühl, Michael, Kestler, Hans A.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514755/