A Novel Mutation of DAX-1 Associated with Secretory Azoospermia

Secretory azoospermia is a severe form of male infertility caused by unknown factors. DAX-1 is predominantly expressed in mammalian reproductive tissues and plays an important role in spermatogenesis because Dax-1 knockout male mice show spermatogenesis defects. To examine whether DAX-1 is involved...

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Bibliographic Details
Main Authors: Mou, Lisha, Xie, Nie, Yang, Lihua, Liu, Yuchen, Diao, Ruiying, Cai, Zhiming, Li, Honggang, Gui, Yaoting
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514677/