Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico

The magnitude of Leptospira exposure in rural Mexico is largely unknown. We sought to determine the seroprevalence of Leptospira IgG antibodies in adults in rural Durango, Mexico, and to determine the sociodemographic, behavioral, and housing characteristics of the subjects associated with Leptospir...

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Main Authors:	Alvarado-Esquivel, Cosme, Sánchez-Anguiano, Luis Francisco, Hernández-Tinoco, Jesús
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512560/

id	pubmed-4512560
recordtype	oai_dc
spelling	pubmed-45125602015-08-03 Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico Alvarado-Esquivel, Cosme Sánchez-Anguiano, Luis Francisco Hernández-Tinoco, Jesús Research Article The magnitude of Leptospira exposure in rural Mexico is largely unknown. We sought to determine the seroprevalence of Leptospira IgG antibodies in adults in rural Durango, Mexico, and to determine the sociodemographic, behavioral, and housing characteristics of the subjects associated with Leptospira seropositivity. We performed a cross-sectional study in 282 adults living in rural Durango, Mexico. Sera from participants were analyzed for Leptospira IgG antibodies using a commercially available enzyme immunoassay. Seroprevalence association with the characteristics of the subjects was analyzed by bivariate and multivariate analyses. Of the 282 rural subjects (42.91 ± 17.53 years old) studied, 44 (15.6%) had anti-Leptospira IgG antibodies. Seropositivity to Leptospira was not associated with gender, educational level, employment, socioeconomic status, contact with animals or soil, or type of floors at home. In contrast, multivariate analysis showed that Leptospira exposure was associated with national trips (OR = 2.09; 95% CI: 1.05–4.16; P = 0.03) and poor education of the head of the family (OR = 2.96; 95% CI: 1.51–5.78; P = 0.001). We demonstrated serological evidence of Leptospira exposure in adults in rural northern Mexico. The contributing factors associated with Leptospira exposure found in the present study may be useful for optimal planning of preventive measures against Leptospira infection. Hindawi Publishing Corporation 2015 2015-07-09 /pmc/articles/PMC4512560/ /pubmed/26240822 http://dx.doi.org/10.1155/2015/460578 Text en Copyright © 2015 Cosme Alvarado-Esquivel et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Alvarado-Esquivel, Cosme Sánchez-Anguiano, Luis Francisco Hernández-Tinoco, Jesús
spellingShingle	Alvarado-Esquivel, Cosme Sánchez-Anguiano, Luis Francisco Hernández-Tinoco, Jesús Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico
author_facet	Alvarado-Esquivel, Cosme Sánchez-Anguiano, Luis Francisco Hernández-Tinoco, Jesús
author_sort	Alvarado-Esquivel, Cosme
title	Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico
title_short	Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico
title_full	Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico
title_fullStr	Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico
title_full_unstemmed	Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico
title_sort	seroepidemiology of leptospira exposure in general population in rural durango, mexico
description	The magnitude of Leptospira exposure in rural Mexico is largely unknown. We sought to determine the seroprevalence of Leptospira IgG antibodies in adults in rural Durango, Mexico, and to determine the sociodemographic, behavioral, and housing characteristics of the subjects associated with Leptospira seropositivity. We performed a cross-sectional study in 282 adults living in rural Durango, Mexico. Sera from participants were analyzed for Leptospira IgG antibodies using a commercially available enzyme immunoassay. Seroprevalence association with the characteristics of the subjects was analyzed by bivariate and multivariate analyses. Of the 282 rural subjects (42.91 ± 17.53 years old) studied, 44 (15.6%) had anti-Leptospira IgG antibodies. Seropositivity to Leptospira was not associated with gender, educational level, employment, socioeconomic status, contact with animals or soil, or type of floors at home. In contrast, multivariate analysis showed that Leptospira exposure was associated with national trips (OR = 2.09; 95% CI: 1.05–4.16; P = 0.03) and poor education of the head of the family (OR = 2.96; 95% CI: 1.51–5.78; P = 0.001). We demonstrated serological evidence of Leptospira exposure in adults in rural northern Mexico. The contributing factors associated with Leptospira exposure found in the present study may be useful for optimal planning of preventive measures against Leptospira infection.
publisher	Hindawi Publishing Corporation
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512560/
_version_	1613251327731695616

Seroepidemiology of Leptospira Exposure in General Population in Rural Durango, Mexico

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