Enhancing Cardiac Triacylglycerol Metabolism Improves Recovery From Ischemic Stress

Elevated cardiac triacylglycerol (TAG) content is traditionally equated with cardiolipotoxicity and suggested to be a culprit in cardiac dysfunction. However, previous work demonstrated that myosin heavy-chain–mediated cardiac-specific overexpression of diacylglycerol transferase 1 (MHC-DGAT1), the...

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Bibliographic Details
Main Authors: Kolwicz, Stephen C., Liu, Li, Goldberg, Ira J., Tian, Rong
Format: Online
Language:English
Published: American Diabetes Association 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512225/