Perilipin 5–Driven Lipid Droplet Accumulation in Skeletal Muscle Stimulates the Expression of Fibroblast Growth Factor 21
Perilipin 5 (PLIN5) is a lipid droplet protein and is highly expressed in oxidative tissue. Expression of the PLIN5 gene is regulated by peroxisome proliferator–activated receptor-α, fasting, and exercise. However, the effect of increased muscle PLIN5 expression on whole-body energy homeostasis rema...
Main Authors: | Harris, Lydia-Ann L.S., Skinner, James R., Shew, Trevor M., Pietka, Terri A., Abumrad, Nada A., Wolins, Nathan E. |
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Format: | Online |
Language: | English |
Published: |
American Diabetes Association
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512215/ |
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