Antibiotic resistance and integrons in Shiga toxin-producing Escherichia coli (STEC)
Shiga toxin-producing Escherichia coli (STEC) cause hemorrhagic colitis (HC) and hemolytic-uremic syndrome in humans (HUS). Cattle are the main reservoir of STEC and transmission to humans occurs through contaminated food and water. Antibiotics are used in pig production systems to combat disease a...
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Sociedade Brasileira de Microbiologia
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512044/ |
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pubmed-45120442015-07-28 Antibiotic resistance and integrons in Shiga toxin-producing Escherichia coli (STEC) Colello, Rocío Etcheverría, Analía I. Conza, Jose A. Di Gutkind, Gabriel O. Padola, Nora L. Review Shiga toxin-producing Escherichia coli (STEC) cause hemorrhagic colitis (HC) and hemolytic-uremic syndrome in humans (HUS). Cattle are the main reservoir of STEC and transmission to humans occurs through contaminated food and water. Antibiotics are used in pig production systems to combat disease and improve productivity and play a key role in the dissemination of antibiotic resistance genes to the bacteria. Integrons have been identified in resistant bacteria allowing for the acquisition and dissemination of antibiotic resistance genes. STEC strains isolated from humans and animals have developed antibiotic resistance. In our laboratory, 21 non-157 STEC strains isolated from pigs were analyzed to detect class 1 and 2 integrons by PCR. Eight carried integrons, 7 of them harbored intl2. In another study 545 STEC strains were also analyzed for the presence of intl1 and intl2 . Strains carrying intl1 belonged to isolates from environment (n = 1), chicken hamburger (n = 2), dairy calves (n = 4) and pigs (n = 8). Two strains isolated from pigs harbored intl2 and only one intl1 / intl2 , highlighting the presence of intl2 in pigs. The selection for multiresistant strains may contribute to the emergence of antibiotic resistant pathogens and facilitate the spreading of the mobile resistance elements to other bacteria. Sociedade Brasileira de Microbiologia 2015-03-01 /pmc/articles/PMC4512044/ /pubmed/26221083 http://dx.doi.org/10.1590/S1517-838246120130698 Text en Copyright © 2015, Sociedade Brasileira de Microbiologia All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License CC BY-NC. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Colello, Rocío Etcheverría, Analía I. Conza, Jose A. Di Gutkind, Gabriel O. Padola, Nora L. |
| spellingShingle |
Colello, Rocío Etcheverría, Analía I. Conza, Jose A. Di Gutkind, Gabriel O. Padola, Nora L. Antibiotic resistance and integrons in Shiga toxin-producing Escherichia coli (STEC) |
| author_facet |
Colello, Rocío Etcheverría, Analía I. Conza, Jose A. Di Gutkind, Gabriel O. Padola, Nora L. |
| author_sort |
Colello, Rocío |
| title |
Antibiotic resistance and integrons in Shiga toxin-producing Escherichia coli
(STEC)
|
| title_short |
Antibiotic resistance and integrons in Shiga toxin-producing Escherichia coli
(STEC)
|
| title_full |
Antibiotic resistance and integrons in Shiga toxin-producing Escherichia coli
(STEC)
|
| title_fullStr |
Antibiotic resistance and integrons in Shiga toxin-producing Escherichia coli
(STEC)
|
| title_full_unstemmed |
Antibiotic resistance and integrons in Shiga toxin-producing Escherichia coli
(STEC)
|
| title_sort |
antibiotic resistance and integrons in shiga toxin-producing escherichia coli
(stec) |
| description |
Shiga toxin-producing Escherichia coli
(STEC) cause hemorrhagic colitis (HC) and hemolytic-uremic syndrome in humans (HUS). Cattle are the main reservoir of STEC and transmission to humans occurs through contaminated food and water. Antibiotics are used in pig production systems to combat disease and improve productivity and play a key role in the dissemination of antibiotic resistance genes to the bacteria. Integrons have been identified in resistant bacteria allowing for the acquisition and dissemination of antibiotic resistance genes. STEC strains isolated from humans and animals have developed antibiotic resistance. In our laboratory, 21 non-157 STEC strains isolated from pigs were analyzed to detect class 1 and 2 integrons by PCR. Eight carried integrons, 7 of them harbored intl2.
In another study 545 STEC strains were also analyzed for the presence of intl1
and intl2
. Strains carrying intl1
belonged to isolates from environment (n = 1), chicken hamburger (n = 2), dairy calves (n = 4) and pigs (n = 8). Two strains isolated from pigs harbored intl2
and only one intl1
/
intl2
, highlighting the presence of intl2
in pigs. The selection for multiresistant strains may contribute to the emergence of antibiotic resistant pathogens and facilitate the spreading of the mobile resistance elements to other bacteria.
|
| publisher |
Sociedade Brasileira de Microbiologia |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512044/ |
| _version_ |
1613251087739912192 |