Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines

Oxidative stress is considered a causative factor in carcinogenesis, but also in the development of resistance to current chemotherapies. The appropriate usage of redox-modulating compounds is limited by the lack of knowledge of their impact on specific molecular pathways. Increased levels of the IK...

Full description

Bibliographic Details
Main Authors: Mukawera, Espérance, Chartier, Stefany, Williams, Virginie, Pagano, Patrick J., Lapointe, Réjean, Grandvaux, Nathalie
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511630/