Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules

Supramolecular self-assembly offers routes to challenging architectures on the molecular and macroscopic scale. Coupled with microfluidics it has been used to make microcapsules—where a 2D sheet is shaped in 3D, encapsulating the volume within. In this paper, a versatile methodology to direct the ac...

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Main Authors:	Parker, Richard M, Zhang, Jing, Zheng, Yu, Coulston, Roger J, Smith, Clive A, Salmon, Andrew R, Yu, Ziyi, Scherman, Oren A, Abell, Chris
Format:	Online
Language:	English
Published:	BlackWell Publishing Ltd 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511391/

id	pubmed-4511391
recordtype	oai_dc
spelling	pubmed-45113912015-07-24 Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules Parker, Richard M Zhang, Jing Zheng, Yu Coulston, Roger J Smith, Clive A Salmon, Andrew R Yu, Ziyi Scherman, Oren A Abell, Chris Full Papers Supramolecular self-assembly offers routes to challenging architectures on the molecular and macroscopic scale. Coupled with microfluidics it has been used to make microcapsules—where a 2D sheet is shaped in 3D, encapsulating the volume within. In this paper, a versatile methodology to direct the accumulation of capsule-forming components to the droplet interface using electrostatic interactions is described. In this approach, charged copolymers are selectively partitioned to the microdroplet interface by a complementary charged surfactant for subsequent supramolecular cross-linking via cucurbit[8]uril. This dynamic assembly process is employed to selectively form both hollow, ultrathin microcapsules and solid microparticles from a single solution. The ability to dictate the distribution of a mixture of charged copolymers within the microdroplet, as demonstrated by the single-step fabrication of distinct core–shell microcapsules, gives access to a new generation of innovative self-assembled constructs. BlackWell Publishing Ltd 2015-07 2015-05-26 /pmc/articles/PMC4511391/ /pubmed/26213532 http://dx.doi.org/10.1002/adfm.201501079 Text en © 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Parker, Richard M Zhang, Jing Zheng, Yu Coulston, Roger J Smith, Clive A Salmon, Andrew R Yu, Ziyi Scherman, Oren A Abell, Chris
spellingShingle	Parker, Richard M Zhang, Jing Zheng, Yu Coulston, Roger J Smith, Clive A Salmon, Andrew R Yu, Ziyi Scherman, Oren A Abell, Chris Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules
author_facet	Parker, Richard M Zhang, Jing Zheng, Yu Coulston, Roger J Smith, Clive A Salmon, Andrew R Yu, Ziyi Scherman, Oren A Abell, Chris
author_sort	Parker, Richard M
title	Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules
title_short	Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules
title_full	Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules
title_fullStr	Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules
title_full_unstemmed	Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules
title_sort	electrostatically directed self-assembly of ultrathin supramolecular polymer microcapsules
description	Supramolecular self-assembly offers routes to challenging architectures on the molecular and macroscopic scale. Coupled with microfluidics it has been used to make microcapsules—where a 2D sheet is shaped in 3D, encapsulating the volume within. In this paper, a versatile methodology to direct the accumulation of capsule-forming components to the droplet interface using electrostatic interactions is described. In this approach, charged copolymers are selectively partitioned to the microdroplet interface by a complementary charged surfactant for subsequent supramolecular cross-linking via cucurbit[8]uril. This dynamic assembly process is employed to selectively form both hollow, ultrathin microcapsules and solid microparticles from a single solution. The ability to dictate the distribution of a mixture of charged copolymers within the microdroplet, as demonstrated by the single-step fabrication of distinct core–shell microcapsules, gives access to a new generation of innovative self-assembled constructs.
publisher	BlackWell Publishing Ltd
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511391/
_version_	1613250810438746112

Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules

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