HDAC4 is required for inflammation-associated thermal hypersensitivity
Transcriptional alterations are characteristic of persistent pain states, but the key regulators remain elusive. HDAC4 is a transcriptional corepressor that has been linked to synaptic plasticity and neuronal excitability, mechanisms that may be involved in peripheral and central sensitization. Usin...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Federation of American Societies for Experimental Biology
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511203/ |