Painful, degenerating intervertebral discs up-regulate neurite sprouting and CGRP through nociceptive factors

Intervertebral disc degeneration (IVD) can result in chronic low back pain, a common cause of morbidity and disability. Inflammation has been associated with IVD degeneration, however the relationship between inflammatory factors and chronic low back pain remains unclear. Furthermore, increased leve...

Full description

Bibliographic Details
Main Authors: Krock, Emerson, Rosenzweig, Derek H, Chabot-Doré, Anne-Julie, Jarzem, Peter, Weber, Michael H, Ouellet, Jean A, Stone, Laura S, Haglund, Lisbet
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508160/