Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

Hyperhomocysteinemia (HHcy) leads to several clinical manifestations including hepatic fibrosis. Excess deposition of extracellular matrix (ECM) components including collagen is the eponymous lesion of liver fibrosis. In this study, we demonstrated that elevated concentration of Hcy induced the expr...

Full description

Bibliographic Details
Main Authors: Lei, Wenjing, Long, Yanjun, Li, Shuang, Liu, Ze, Zhu, Fengxin, Hou, Fan Fan, Nie, Jing
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508059/