Asymmetric synthesis of N-allylic indoles via regio- and enantioselective allylation of aryl hydrazines

The asymmetric synthesis of N-allylic indoles is important for natural product synthesis and pharmaceutical research. The regio- and enantioselective N-allylation of indoles is a true challenge due to the favourable C3-allylation. We develop here a new strategy to the asymmetric synthesis of N-allyl...

Full description

Bibliographic Details
Main Authors: Xu, Kun, Gilles, Thomas, Breit, Bernhard
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506507/