Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance
Adiponectin plays a key role in the regulation of the whole-body energy homeostasis by modulating glucose and lipid metabolism. Although obesity-induced reduction of adiponectin expression is primarily ascribed to a transcriptional regulation failure, the underlying mechanisms are largely undefined....
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506505/ |