Ability of the Encephalitic Arbovirus Semliki Forest Virus To Cross the Blood-Brain Barrier Is Determined by the Charge of the E2 Glycoprotein

Semliki Forest virus (SFV) provides a well-characterized model system to study the pathogenesis of virus encephalitis. Several studies have used virus derived from the molecular clone SFV4. SFV4 virus does not have the same phenotype as the closely related L10 or the prototype virus from which its m...

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Bibliographic Details
Main Authors: Ferguson, Mhairi C., Saul, Sirle, Fragkoudis, Rennos, Weisheit, Sabine, Cox, Jonathan, Patabendige, Adjanie, Sherwood, Karen, Watson, Mick, Merits, Andres, Fazakerley, John K.
Format: Online
Language:English
Published: American Society for Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505677/