Delimiting Allelic Imbalance of TYMS by Allele-Specific Analysis

Allelic imbalance of thymidylate synthase (TYMS) is attributed to polymorphisms in the 5′- and 3′-untranslated region (UTR). These polymorphisms have been related to the risk of suffering different cancers, for example leukemia, breast or gastric cancer, and response to different drugs, among which...

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Bibliographic Details
Main Authors: Balboa-Beltrán, Emilia, Cruz, Raquel, Carracedo, Angel, Barros, Francisco
Format: Online
Language:English
Published: Wolters Kluwer Health 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504634/