Delimiting Allelic Imbalance of TYMS by Allele-Specific Analysis
Allelic imbalance of thymidylate synthase (TYMS) is attributed to polymorphisms in the 5′- and 3′-untranslated region (UTR). These polymorphisms have been related to the risk of suffering different cancers, for example leukemia, breast or gastric cancer, and response to different drugs, among which...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Wolters Kluwer Health
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504634/ |