SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation

Synapsins are key components of the presynaptic neurotransmitter release machinery. Their main role is to cluster synaptic vesicles (SVs) to each other and anchor them to the actin cytoskeleton to establish the reserve vesicle pool, and then release them in response to appropriate membrane depolariz...

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Bibliographic Details
Main Authors: Tang, Leo T. -H., Craig, Tim J., Henley, Jeremy M.
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504226/