SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation
Synapsins are key components of the presynaptic neurotransmitter release machinery. Their main role is to cluster synaptic vesicles (SVs) to each other and anchor them to the actin cytoskeleton to establish the reserve vesicle pool, and then release them in response to appropriate membrane depolariz...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504226/ |