Pro-Inflammatory Cytokine IL-1β Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma

Pro-Inflammatory Cytokine IL-1β Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma

Chronic inflammation contributes to tumor development through the induction of oncogenic mutations, genomic instability, early tumor promotion, and enhanced angiogenesis. Here, we report that IL-1 receptor 1 (IL-1R1) was expressed in 40 of 41 human tongue squamous cell carcinomas (TSCC). IL-1β up-re...

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Bibliographic Details
Main Authors: Sun, Yi, Zhu, Demao, Wang, Guihua, Wang, Di, Zhou, Huashan, Liu, Xueting, Jiang, Manli, Liao, Lingjuan, Zhou, Zhiguang, Hu, Jinyue
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503771/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503771/

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