Serum UCH-L1 as a Novel Biomarker to Predict Neuronal Apoptosis Following Deep Hypothermic Circulatory Arrest

Background: Deep hypothermic circulatory arrest (DHCA) has been used in cardiac surgery involving infant complex congenital heart disease and aortic dissection. DHCA carries a risk of neuronal apoptotic death in brain. Serum ubiquitin C-terminal hydrolase L1 (UCH-L1) level is elevated in a number of...

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Bibliographic Details
Main Authors: Zhang, Ya-Ping, Zhu, Yao-Bin, Duan, Dayue Darrel, Fan, Xiang-Ming, He, Yan, Su, Jun-Wu, Liu, Ying-Long
Format: Online
Language:English
Published: Ivyspring International Publisher 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502062/