An ELMO2-RhoG-ILK network modulates microtubule dynamics
Complexes that contain ELMO2, RhoG, and integrin-linked kinase are required to maintain microtubule stability. Mechanistically, these complexes are involved in activation of Rac1, which in turn interferes with the destabilizing activity of stathmin. In addition, these complexes also mediate activati...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501367/ |