An ELMO2-RhoG-ILK network modulates microtubule dynamics

Complexes that contain ELMO2, RhoG, and integrin-linked kinase are required to maintain microtubule stability. Mechanistically, these complexes are involved in activation of Rac1, which in turn interferes with the destabilizing activity of stathmin. In addition, these complexes also mediate activati...

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Bibliographic Details
Main Authors: Jackson, Bradley C., Ivanova, Iordanka A., Dagnino, Lina
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501367/