Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness

Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness

Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either the tuberous sclerosis complex 1 or 2 (TSC1 or TSC2) genes. While allosteric inhibition of the mechanistic target of r...

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Bibliographic Details
Main Authors: Ruiz de Garibay, Gorka, Herranz, Carmen, Llorente, Alicia, Boni, Jacopo, Serra-Musach, Jordi, Mateo, Francesca, Aguilar, Helena, Gómez-Baldó, Laia, Petit, Anna, Vidal, August, Climent, Fina, Hernández-Losa, Javier, Cordero, Álex, González-Suárez, Eva, Sánchez-Mut, José Vicente, Esteller, Manel, Llatjós, Roger, Varela, Mar, López, José Ignacio, García, Nadia, Extremera, Ana I., Gumà, Anna, Ortega, Raúl, Plà, María Jesús, Fernández, Adela, Pernas, Sònia, Falo, Catalina, Morilla, Idoia, Campos, Miriam, Gil, Miguel, Román, Antonio, Molina-Molina, María, Ussetti, Piedad, Laporta, Rosalía, Valenzuela, Claudia, Ancochea, Julio, Xaubet, Antoni, Casanova, Álvaro, Pujana, Miguel Angel
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500593/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500593/

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