Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

Prevention efforts for respiratory syncytial virus (RSV) have been advanced due to the recent isolation and characterization of antibodies that specifically recognize the prefusion conformation of the RSV fusion (F) glycoprotein. These potently neutralizing antibodies are in clinical development for...

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Bibliographic Details
Main Authors: Gilman, Morgan S. A., Moin, Syed M., Mas, Vicente, Chen, Man, Patel, Nita K., Kramer, Kari, Zhu, Qing, Kabeche, Stephanie C., Kumar, Azad, Palomo, Concepción, Beaumont, Tim, Baxa, Ulrich, Ulbrandt, Nancy D., Melero, José A., Graham, Barney S., McLellan, Jason S.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498696/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498696/

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