Neutrophil Extracellular Traps are Involved in the Innate Immune Response to Infection with Leptospira

NETosis is a process by which neutrophils extrude their DNA together with bactericidal proteins that trap and/or kill pathogens. In the present study, we evaluated the ability of Leptospira spp. to induce NETosis using human ex vivo and murine in vivo models. Microscopy and fluorometric studies show...

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Bibliographic Details
Main Authors: Scharrig, Emilia, Carestia, Agostina, Ferrer, María F., Cédola, Maia, Pretre, Gabriela, Drut, Ricardo, Picardeau, Mathieu, Schattner, Mirta, Gómez, Ricardo M.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498591/