Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses

Background. Human noroviruses are the leading cause of acute viral gastroenteritis, justifying vaccine development despite a limited understanding of strain immunity. After genogroup I (GI).1 norovirus infection and immunization, blockade antibody titers to multiple virus-like particles (VLPs) incre...

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Main Authors:	Lindesmith, Lisa C., Beltramello, Martina, Swanstrom, Jesica, Jones, Taylor A., Corti, Davide, Lanzavecchia, Antonio, Baric, Ralph S.
Format:	Online
Language:	English
Published:	Oxford University Press 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498284/

id	pubmed-4498284
recordtype	oai_dc
spelling	pubmed-44982842015-07-15 Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses Lindesmith, Lisa C. Beltramello, Martina Swanstrom, Jesica Jones, Taylor A. Corti, Davide Lanzavecchia, Antonio Baric, Ralph S. Major Articles Background. Human noroviruses are the leading cause of acute viral gastroenteritis, justifying vaccine development despite a limited understanding of strain immunity. After genogroup I (GI).1 norovirus infection and immunization, blockade antibody titers to multiple virus-like particles (VLPs) increase, suggesting that GI cross-protection may occur. Oxford University Press 2015-07-01 /pmc/articles/PMC4498284/ /pubmed/26180833 http://dx.doi.org/10.1093/ofid/ofv084 Text en © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Lindesmith, Lisa C. Beltramello, Martina Swanstrom, Jesica Jones, Taylor A. Corti, Davide Lanzavecchia, Antonio Baric, Ralph S.
spellingShingle	Lindesmith, Lisa C. Beltramello, Martina Swanstrom, Jesica Jones, Taylor A. Corti, Davide Lanzavecchia, Antonio Baric, Ralph S. Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses
author_facet	Lindesmith, Lisa C. Beltramello, Martina Swanstrom, Jesica Jones, Taylor A. Corti, Davide Lanzavecchia, Antonio Baric, Ralph S.
author_sort	Lindesmith, Lisa C.
title	Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses
title_short	Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses
title_full	Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses
title_fullStr	Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses
title_full_unstemmed	Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses
title_sort	serum immunoglobulin a cross-strain blockade of human noroviruses
description	Background. Human noroviruses are the leading cause of acute viral gastroenteritis, justifying vaccine development despite a limited understanding of strain immunity. After genogroup I (GI).1 norovirus infection and immunization, blockade antibody titers to multiple virus-like particles (VLPs) increase, suggesting that GI cross-protection may occur.
publisher	Oxford University Press
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498284/
_version_	1613246388158595072

Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses

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