Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme

Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme

To provide tight spatiotemporal signaling control, the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) holoenzyme typically nucleates a macromolecular complex or a “PKA signalosome.” Using the RIIβ holoenzyme as a prototype, we show how autophosphorylation/dephosphorylation of t...

Full description

Bibliographic Details
Main Authors: Zhang, Ping, Knape, Matthias J., Ahuja, Lalima G., Keshwani, Malik M., King, Charles C., Sastri, Mira, Herberg, Friedrich W., Taylor, Susan S.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497662/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497662/

Similar Items