On the Role of Pre- and Post-Electron-Transfer Steps in the SmI2/Amine/H2O-Mediated Reduction of Esters: New Mechanistic Insights and Kinetic Studies
The mechanism of the SmI2-mediated reduction of unactivated esters has been studied using a combination of kinetic, radical clocks and reactivity experiments. The kinetic data indicate that all reaction components (SmI2, amine, H2O) are involved in the rate equation and that electron transfer is fac...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
WILEY-VCH Verlag
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497321/ |