Initial Events in Bacterial Transcription Initiation

Transcription initiation is a highly regulated step of gene expression. Here, we discuss the series of large conformational changes set in motion by initial specific binding of bacterial RNA polymerase (RNAP) to promoter DNA and their relevance for regulation. Bending and wrapping of the upstream du...

Full description

Bibliographic Details
Main Authors: Ruff, Emily F., Record, M. Thomas, Artsimovitch, Irina
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496709/