Manipulation of prostate cancer metastasis by locus-specific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase

Manipulation of prostate cancer metastasis by locus-specific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase

Prostate cancer is the most commonly diagnosed non-cutaneous cancer and one of the leading causes of cancer death for North American men. Whereas localized prostate cancer can be cured, there is currently no cure for metastatic prostate cancer. Here we report a novel approach that utilizes designed...

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Bibliographic Details
Main Authors: Li, Ke, Pang, Jun, Cheng, Huaiyan, Liu, Wei-Peng, Di, Jin-Ming, Xiao, Heng-Jun, Luo, Yun, Zhang, Hao, Huang, Wen-Tao, Chen, Ming-Kun, Li, Liao-Yuan, Shao, Chun-Kui, Feng, Ying-Hong, Gao, Xin
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496338/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496338/

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