PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis

Autophagy plays a critical role in the progression of nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). Protein tyrosine phosphatase receptor type O (PTPRO) was recently identified as a tumor suppressor, but little is known about its role in NASH. Here, we investigated the role...

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Bibliographic Details
Main Authors: Zhang, Wenjie, Hou, Jiajie, Wang, Xiaochen, Jiang, Runqiu, Yin, Yin, Ji, Jie, Deng, Lei, Huang, Xingxu, Wang, Ke, Sun, Beicheng
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496227/