Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization

Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization

The expression of members of the Eph family of receptor tyrosine kinases and their ephrin ligands is frequently dysregulated in medulloblastomas. We assessed the expression and functional role of EphB1 in medulloblastoma cell lines and engineered mouse models. mRNA and protein expression profiling s...

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Bibliographic Details
Main Authors: Bhatia, Shilpa, Baig, Nimrah A., Timofeeva, Olga, Pasquale, Elena B., Hirsch, Kellen, MacDonald, Tobey J., Dritschilo, Anatoly, Lee, Yi Chien, Henkemeyer, Mark, Rood, Brian, Jung, Mira, Wang, Xiao-Jing, Kool, Marcel, Rodriguez, Olga, Albanese, Chris, Karam, Sana D.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496193/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496193/

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