Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors

Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors

Colorectal cancer is a major health problem and the second cause of cancer related death in western countries. Signaling pathways that control tissue homeostasis are often deregulated during tumorigenesis and contribute to tumor development. Studies in mouse models have shown that the p38 MAPK pathw...

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Bibliographic Details
Main Authors: Gupta, Jalaj, Igea, Ana, Papaioannou, Marilena, Lopez-Casas, Pedro Pablo, Llonch, Elisabet, Hidalgo, Manuel, Gorgoulis, Vassilis G., Nebreda, Angel R.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496165/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496165/

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