Magnolia Bioactive Constituent 4-O-Methylhonokiol Prevents the Impairment of Cardiac Insulin Signaling and the Cardiac Pathogenesis in High-Fat Diet-Induced Obese Mice

In obesity, cardiac insulin resistance is a putative cause of cardiac hypertrophy and dysfunction. In our previous study, we observed that Magnolia extract BL153 attenuated high-fat-diet (HFD)-induced cardiac pathogenic changes. In this study, we further investigated the protective effects of the BL...

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Bibliographic Details
Main Authors: Zhang, Zhiguo, Chen, Jing, Zhou, Shanshan, Wang, Shudong, Cai, Xiaohong, Conklin, Daniel J., Kim, Ki-Soo, Kim, Ki Ho, Tan, Yi, Zheng, Yang, Kim, Young Heui, Cai, Lu
Format: Online
Language:English
Published: Ivyspring International Publisher 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495406/