Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets

Background: Drug development in sarcoma has been hampered by the rarity and heterogeneity of the disease and lack of predictive biomarkers to therapies. We assessed protein expression and gene alterations in a large number of bone and soft tissue sarcomas in order to categorize the molecular alterat...

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Bibliographic Details
Main Authors: Movva, Sujana, Wen, Wenhsiang, Chen, Wangjuh, Millis, Sherri Z., Gatalica, Zoran, Reddy, Sandeep, von Mehren, Margaret, Van Tine, Brian A.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494935/