VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity

VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity

VAMP8 is associated with the recycling endosome compartment rather than with cytotoxic granules and is required for a fusion step between recycling endosomes and the plasma membrane that brings syntaxin-11 to the immune synapse for cytotoxic granule exocytosis.

Bibliographic Details
Main Authors: Marshall, Misty R., Pattu, Varsha, Halimani, Mahantappa, Maier-Peuschel, Monika, Müller, Martha-Lena, Becherer, Ute, Hong, Wanjin, Hoth, Markus, Tschernig, Thomas, Bryceson, Yenan T., Rettig, Jens
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493996/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493996/

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