DSP-1053, a novel serotonin reuptake inhibitor with 5-HT1A partial agonistic activity, displays fast antidepressant effect with minimal undesirable effects in juvenile rats

Enhancement of serotonergic neurotransmission has been the main stream of treatment for patients with depression. However, delayed therapeutic onset and undesirable side effects are major drawbacks for conventional serotonin reuptake inhibitors. Here, we show that DSP-1053, a novel serotonin reuptak...

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Bibliographic Details
Main Authors: Kato, Taro, Matsumoto, Yuji, Yamamoto, Masanori, Matsumoto, Kenji, Baba, Satoko, Nakamichi, Keiko, Matsuda, Harumi, Nishimuta, Haruka, Yabuuchi, Kazuki
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492758/