Dual Inhibitors Against Topoisomerases and Histone Deacetylases

Topoisomerases and histone deacetylases (HDACs) are considered as important therapeutic targets for a wide range of cancers, due to their association with the initiation, proliferation and survival of cancer cells. Topoisomerases are involved in the cleavage and religation processes of DNA, while HD...

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Bibliographic Details
Main Author: Seo, Young Ho
Format: Online
Language:English
Published: Korean Society of Cancer Prevention 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492363/