A Plasmacytoid Dendritic Cells-Type I Interferon Axis Is Critically Implicated in the Pathogenesis of Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease that is characterized by the generation of immune responses to various nuclear components. Impaired clearance of apoptotic cells and loss of tolerance to self-antigens are involved both in the initiation and in the propagation of...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490545/ |