Treatment of Prion Disease with Heterologous Prion Proteins

Prion diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy in cattle, and scrapie in sheep are fatal neurodegenerative diseases for which there is no effective treatment. The pathology of these diseases involves the conversion of a protease sensitive form of the cel...

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Bibliographic Details
Main Authors: Skinner, Pamela J., Kim, Hyeon O., Bryant, Damani, Kinzel, Nikilyn J., Reilly, Cavan, Priola, Suzette A., Ward, Anne E., Goodman, Patricia A., Olson, Katherine, Seelig, Davis M.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489745/