Application of CRISPR/Cas9 for biomedical discoveries

The Clustered Regions of Interspersed Palindromic Repeats-Cas9 (CRISPR/Cas9), a viral defense system found in bacteria and archaea, has emerged as a tour de force genome editing tool. The CRISPR/Cas9 system is much easier to customize and optimize because the site selection for DNA cleavage is guide...

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Bibliographic Details
Main Authors: Riordan, Sean M., Heruth, Daniel P., Zhang, Li Q., Ye, Shui Qing
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487574/