New OprM structure highlighting the nature of the N-terminal anchor

Among the different mechanisms used by bacteria to resist antibiotics, active efflux plays a major role. In Gram-negative bacteria, active efflux is carried out by tripartite efflux pumps that form a macromolecular assembly spanning both membranes of the cellular wall. At the outer membrane level, a well-...

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Bibliographic Details
Main Authors: Monlezun, Laura, Phan, Gilles, Benabdelhak, Houssain, Lascombe, Marie-Bernard, Enguéné, Véronique Y. N., Picard, Martin, Broutin, Isabelle
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486845/