New OprM structure highlighting the nature of the N-terminal anchor
Among the different mechanisms used by bacteria to resist antibiotics, active efflux plays a major role. In Gram-negative bacteria, active efflux is carried out by tripartite efflux pumps that form a macromolecular assembly spanning both membranes of the cellular wall. At the outer membrane level, a well-...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486845/ |