Endothelial CXCR7 Regulates Breast Cancer Metastasis

Endothelial CXCR7 Regulates Breast Cancer Metastasis

Atypical chemokine receptor CXCR7 (ACKR3) functions as a scavenger receptor for chemokine CXCL12, a molecule that promotes multiple steps in tumor growth and metastasis in breast cancer and multiple other malignancies. While normal vascular endothelium expresses low levels of CXCR7, marked upregulat...

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Bibliographic Details
Main Authors: Stacer, Amanda C., Fenner, Joseph, Cavnar, Stephen P., Xiao, Annie, Zhao, Shuang, Chang, S. Laura, Salomonnson, Anna, Luker, Kathryn E., Luker, Gary D.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486335/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486335/

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