Morphology and Progression in Primary Varicose Vein Disorder Due to 677C>T and 1298A>C Variants of MTHFR

•MTHFR polymorphism c.677C>T characterizes axial trunk and c.1298A>C perforator type morphology in primary varicose veins.•Mutant genotypes are associated with complicated phenotypes of the disease.•Genetic hint for distinct perforator type morphology associating further with congestive (CEAP...

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Main Authors: Wilmanns, Christoph, Cooper, Alexis, Wockner, Leesa, Katsandris, Sotirios, Glaser, Nadine, Meyer, Alexander, Bartsch, Oliver, Binder, Harald, Walter, Paul Karl, Zechner, Ulrich
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484817/