Biomarkers Can Identify Pulmonary Tuberculosis in HIV-infected Drug Users Months Prior to Clinical Diagnosis

Biomarkers Can Identify Pulmonary Tuberculosis in HIV-infected Drug Users Months Prior to Clinical Diagnosis

•A predictive signature was detected in ex vivo PBMCs of HIV-infected drug users up to 8 months prior to clinical TB diagnosis;•Combined expression of IL13 and AIRE had the highest discriminatory power to identify cases months prior to TB diagnosis.•Cases expressing IL13 had a gene expression patter...

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Bibliographic Details
Main Authors: Sloot, Rosa, Schim van der Loeff, Maarten F., van Zwet, Erik W., Haks, Mariëlle C., Keizer, Sytze T., Scholing, Maarten, Ottenhoff, Tom H.M., Borgdorff, Martien W., Joosten, Simone A.
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484511/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484511/

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