MP-12 virus containing the clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters

MP-12 virus containing the clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters

Rift Valley fever virus (RVFV; Bunyaviridae, Phlebovirus) causes a range of illnesses that include retinitis, fulminant hepatitis, neurologic disease, and hemorrhagic fever. In hospitalized individuals, case fatality rates can be as high as 10–20%. There are no vaccines or antivirals approved for hu...

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Bibliographic Details
Main Authors: Gowen, Brian B., Westover, Jonna B., Sefing, Eric J., Bailey, Kevin W., Nishiyama, Shoko, Wandersee, Luci, Scharton, Dionna, Jung, Kie-Hoon, Ikegami, Tetsuro
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484224/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484224/

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